COMPARE · Data as of August 21, 2026
EXEL vs INSM
Verdict: Side-by-side breakdown using the Bull Rankings model. EXEL scored 74.1, INSM scored 38.6 — EXEL leads.
Compare another set
EXEL
Exelixis, Inc.
74.1
$54.08 · $13.4B
fundamentals as of
Score gap
35.5
EXEL leads
INSM
Insmed Incorporated
38.6
$125.77 · $27.5B
fundamentals as of
At a glance · who leads each dimension, on the model's own rules
- Fastest growthINSM+185.8%
- Strongest balance sheetEXEL0.09
- Highest qualityEXEL97 / 100
- Largest discount to fair valueEXEL-42%
Side by side · every name on one set of axes
The model, pillar by pillar (0–100 each)
EXEL
stronger →← stronger
INSM
97
Qualityreturns · margins · balance sheet
11
80
Growthrevenue & earnings expansion
98
53
Valuevaluation vs sector peers
55
INSM is stronger on 2 of 3 pillars.
Fundamentals, head-to-head
EXEL
INSM
$1.2bC+
FCF
-$808mF
+9.2%B
Rev
+185.8%A
0.09B+
D/E
0.98C
17.0xA-
P/E
—
2.56C
PEG
1.09B+
—
P/S
24.1xD
Winner per row is the stronger grade; where grades tie, the better figure breaks it. A true tie or a missing value shows no highlight.
Valuation · DCF cross-check
EXEL
INSM
42% below
Price vs fair valuelower is cheaper
—
~-3%/yr
Growth the price implies10-yr FCF · lower = less priced in
—
+45%
1-yr DCF upside
—
+72%
5-yr DCF upside
—
+118%
10-yr DCF upside
—
The DCF is a cross-check on intrinsic value, separate from the quality-growth score above.
Model signals
EXEL
Why this score
- Buying back stock
- Durable high returns
INSM
Why this score
- Diluting shareholders
The companies
EXELExelixis, Inc.
Why now
Biotechnology · market cap $13.4b. 6% off the 52-week high of $57.57. 17 sell-side analysts rate this a Buy with a mean 1-yr target of $53.00 (implying -2% upside).
Moat
Net margin 35% is exceptional — pricing-power territory rare outside premium software, branded staples, and specialty pharma. ROE 47% — top-decile capital efficiency. Either pricing leverage, low capital intensity, or aggressive buybacks; the durability story depends on which. FCF converts 136% of net income — earnings translate cleanly into cash, a sign that working capital and capex are well-disciplined.
Risk
Trial-readout binary — late-stage clinical trials carry approve/reject outcomes that swing valuation 30%+; the equity is effectively a portfolio of these binary events, not a steady cash-flow business.
INSMInsmed Incorporated
Why now
Biotechnology · market cap $27.5b. Down 41% from 52-week high of $212.75 — deep drawdown territory. Revenue growing +186% — in hypergrowth territory. 22 sell-side analysts rate this a Strong Buy with a mean 1-yr target of $200.05 (implying +59% upside).
Moat
Pharma moat is patent runway + pipeline depth — a single approved molecule funds the next generation of bets. Late-stage trials carry binary readouts that swing valuation 30%+.
Risk
Free cash flow is negative (-$808m) — capital raises or debt issuance likely required; dilution / leverage risk. Currently unprofitable (margin -76.9%) — path to GAAP profitability is the core thesis risk. Down 41% from the 52-week high — the market is pricing in something the screen can't see; verify the bear case before sizing up.
Verdict — model-derived comparison
Generating verdict… typically 5–10 seconds
Not investment advice. The Bull Rankings publishes a quantitative ranking model and accompanying analysis for general informational purposes only. Nothing on this page is a recommendation to buy, sell, or hold any security; nothing is personalized to your circumstances, risk tolerance, or tax situation. Investing carries the risk of loss — invest at your own risk and consider consulting a licensed financial professional before acting on anything you read here. See terms and methodology for full disclosures.
Where EXEL and INSM diverge
On the headline score the gap is 35.5 points in favor of EXEL. They get there differently, though — each leads on a different pillar, so the better pick depends on which you weight.
- QualityEXEL 96.8 · INSM 10.6EXEL +86.2
- GrowthEXEL 80.0 · INSM 97.8INSM +17.8
- ValueEXEL 52.5 · INSM 55.5INSM +3.0
Pillars run 0–100 against sector peers, so a score is a statement about a company relative to its own industry rather than to the other name here. A wide Value gap usually means the market already prices the difference in quality or growth — which is the trade-off this comparison comes down to.